Myc is a gene that regulates the expression of other genes, with important roles in a number of processes including cell death. Myc mutations are very common—over half of human cancers—and understanding its role in tumour cells is a major area of investigation.
Drugs that are normally used to control cholesterol can also trigger tumour cells to self-destruct. Understanding the mechanisms of these drugs could lead to a new tool in the arsenal against cancer—one that is already approved for use in humans, fast-tracking its use in patients.
Led by Linda Penn, PhD, Senior Scientist at Princess Margaret and Tier 1 Canada Research Chair, the Penn Lab is composed of talented, hard-working students, post-doctoral fellows, and staff working together to understand cancer and develop new treatments. Click below to learn more about the people working in the lab and our alumni members.