Myc is a gene that regulates the expression of other genes, with important roles in a number of processes including cell death. Myc mutations are very common—over half of human cancers—and understanding its role in tumour cells is a major area of investigation.
Drugs that are normally used to control cholesterol can also trigger tumour cells to self-destruct. Understanding the mechanisms of these drugs could lead to a new tool in the arsenal against cancer—one that is already approved for use in humans, fast-tracking its use in patients.
Led by Linda Penn, PhD, Senior Scientist at Princess Margaret and Tier 1 Canada Research Chair, the Penn Lab is composed of talented, hard-working students, post-doctoral fellows, and staff working together to understand cancer and develop new treatments. Click below to learn more about the people working in the lab and our alumni members.
View some of our current lab members and alumni