Publications
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins
https://pennlab.ca/wp-content/uploads/2022/03/Graphical-abstract_MYC-PNUTS_NARcompatible.tiff 1 1 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2022/03/Graphical-abstract_MYC-PNUTS_NARcompatible.tiffThe MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase
https://pennlab.ca/wp-content/themes/osmosis/images/empty/thumbnail.jpg 150 150 Penn Lab Penn Lab https://pennlab.ca/wp-content/themes/osmosis/images/empty/thumbnail.jpgMYC protein interactors in gene transcription and cancer
https://pennlab.ca/wp-content/uploads/2021/07/Lourenco_MYC_review.png 605 482 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2021/07/Lourenco_MYC_review.pngIdentifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies
https://pennlab.ca/wp-content/themes/osmosis/images/empty/thumbnail.jpg 150 150 Penn Lab Penn Lab https://pennlab.ca/wp-content/themes/osmosis/images/empty/thumbnail.jpgMevalonate pathway inhibition slows breast cancer metastasis via reduced N-glycosylation abundance and branching
https://pennlab.ca/wp-content/uploads/2021/02/Rosemary_Dolichol.png 396 361 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2021/02/Rosemary_Dolichol.pngStatins as Anticancer Agents in the Era of Precision Medicine
https://pennlab.ca/wp-content/themes/osmosis/images/empty/thumbnail.jpg 150 150 Penn Lab Penn Lab https://pennlab.ca/wp-content/themes/osmosis/images/empty/thumbnail.jpgCyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death
https://pennlab.ca/wp-content/uploads/2020/08/JL_cAMP-paper.png 952 562 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/08/JL_cAMP-paper.pngThe mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma
https://pennlab.ca/wp-content/uploads/2020/07/JL_t414-paper.png 621 267 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/07/JL_t414-paper.pngA pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer
https://pennlab.ca/wp-content/uploads/2020/03/JL_WinSTOP-trial.png 660 896 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/03/JL_WinSTOP-trial.png- 1
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