Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation https://pennlab.ca/wp-content/uploads/2024/08/Graphical-Abstract_BIOPHA_116934-1-1024x717.jpeg 1024 717 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2024/08/Graphical-Abstract_BIOPHA_116934-1-1024x717.jpeg August 26, 2024 August 26, 2024 August 26, 2024 0 …read more
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins https://pennlab.ca/wp-content/uploads/2023/05/Screen-Shot-2023-05-18-at-12.24.29-PM.png 757 671 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2023/05/Screen-Shot-2023-05-18-at-12.24.29-PM.png May 18, 2023 May 18, 2023 May 18, 2023 0 read more
Mevalonate pathway inhibition slows breast cancer metastasis via reduced N-glycosylation abundance and branching https://pennlab.ca/wp-content/uploads/2021/02/Rosemary_Dolichol.png 396 361 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2021/02/Rosemary_Dolichol.png February 21, 2021 February 21, 2021 February 21, 2021 0 read more
Statins as Anticancer Agents in the Era of Precision Medicine https://pennlab.ca/wp-content/uploads/2020/11/Screen-Shot-2020-11-05-at-12.14.41-PM.png 717 688 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/11/Screen-Shot-2020-11-05-at-12.14.41-PM.png November 5, 2020 November 5, 2020 November 5, 2020 0 read more
Cyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death https://pennlab.ca/wp-content/uploads/2020/08/JL_cAMP-paper.png 952 562 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/08/JL_cAMP-paper.png August 26, 2020 August 26, 2020 August 26, 2020 0 read more
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma https://pennlab.ca/wp-content/uploads/2020/07/JL_t414-paper_cropped.png 295 211 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/07/JL_t414-paper_cropped.png July 14, 2020 July 14, 2020 July 14, 2020 0 read more
A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer https://pennlab.ca/wp-content/uploads/2020/03/JL_WinSTOP-trial_square-1024x796.png 1024 796 Penn Lab Penn Lab https://pennlab.ca/wp-content/uploads/2020/03/JL_WinSTOP-trial_square-1024x796.png March 19, 2020 March 19, 2020 March 19, 2020 0 read more